As I mentioned earlier, in the April 1998 edition of the newsletter, Dr. Wolfe seems very concerned about the use of Grepafloxin, in that this quinolone has the potential to dangerously interact with other medications, making it possibly more risky than perhaps other quinolones which may not have this same known profile (these are my words, my interpretations of what he is saying). He says that the FDA made a grave error in not requiring a bold black box warning re these potentially fatal interactions which would warn doctors.

Would they read it or anything else on a package insert - did anyone bother w/ me?? or any of you??

At the very least all quinolones should have more than one black box warning.

(again, my opinion)

To quote part of a paragraph in the article by Dr. Wolfe; " This fluoroquinolone family of antibiotics can cause convulsions, increased intracranial pressure, and psychosis. Fluoroquinolones may also cause central nervous stimulation which may lead to tremors, restlessness, lightheadedness, confusion, or hallucinations. The use of nonsteroidal anti-inflammatory drugs(NSAIDS) such as ibuprofin (Motrin, Motrin IB, Advil and generics) or naproxen (Naprosyn, Aleve and generics) with a fluoroquinolone may increase the risks of central nervous system stimulation and convulsions when used with grepafloxacin"

(grepafloxacin = Raxar)

.Oh yes and the title of this article is Grepafloxacin (Raxar) The Eight Fluoroquinolone Antibiotic" DO NOT USE (WHO NEEDS IT?)

Well, I know that I never needed both Floxin and Cipro, which have altered my life irreparably for the last five years. Today is the fifth anniversary to the day when I took my first dose of Floxin. The only warning given to me by the doctor was that it was very expensive. Boy was she ever right on the $ ! Wish I could buy back the last five years. I was in such agony on the eighth day of treatment, (my 35th birthday). Ambulance to ER next day. So I will be 40 next week and what do they say about being 40?? Life begins....well, I guess I have a week to sort that one out. I thought I might have another child five years ago , but Floxin and then Cipro stopped all prospects of that. Thank God my 2 children are healthy and my husband is, as well, but they deserve me back the way I used to be, unless a miracle happens, which I have never lost hope for or faith in...went down this road less traveled for some reason and if it's to save others from a nightmare, then so be it